With sizing ranging from medium to extra large, and widths from narrow to wide, this is an excellent choice for home wall variety. Set #3 is harder to grip than Set #1 and Set #2.
On vertical walls, this set comes in around V3. The climbing will be a little more difficult at V4 when setting these grips on slightly overhanging 25-degree walls.
On 45-degree walls, this is an excellent set for the advanced climber. You get to engage your thumbs to stay on the pinches. This set feels in the V7+ range on 45-degree walls though they can easily be set on harder boulder problems.
You may also be interested in these other sets of Variety Pinches. Set #1 is the easiest to grip. Set #3 is the hardest.